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Home > Resource Finder > Centre > Facilities and Skills
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Facilities and Skills
Click on the category headings to reveal the facilities and skills available within the Oxford Experimental Cancer Medicine Centre
- Brief description of centre
The aims of the Centre are:- To make basic scientific discoveries in cancer biology and apply them to the development of novel therapies for cancer
- To apply our discoveries to understand the biology of human cancer and develop prognostic or predictive markers
- To facilitate translational research through clinical fellowships with joint laboratory and clinical supervision on projects in the areas selected
- To train scientists and clinicians in cancer biology
- Methodologies to study:
The Oxford Experimental Cancer Medicine Centre has specialist expertise in the following areas: - Angiogenesis
- Pharmacodynamics
- Tumour vasculature and metastasis
- DNA Repair
- Immunotherapy
- Gene Therapy
- Radiation oncology
- Signalling pathways
- In-patient beds
- Day case beds
- Comment
The Oxford Experimental Cancer Medicine Centre makes use of the patient facilities within the Medical Oncology Unit at the Churchill Hospital and will move into a new Cancer Hospital on the same site in 2008. It is part of a tertiary referral centre and the University Hospital within the John Radcliffe Hospitals site, so excellent medical investigation is available for every medical specialty. - Consulting rooms
- Phlebotomy
- Pulse-oximetry
- ECG
- Non-invasive blood pressure monitoring
- Infusion devices
- Chemotherapy administration
- Other
- Pharmacokinetic and pharmacodynamic blood sampling
- Portacath care
- Centrifuge
- Fridges (4oC) for short term storage
- Freezers (-20oC) for short term storage
- Freezers (-20oC) for long term storage (tissue collection)
- Freezers (-80oC)
- Liquid Nitrogen storage system (tissue collection)
- Class II biological safety cabinet (Laminar flow)
- Class III biological safety cabinet
- Flow cytometer
- Plate reader
- Gel electrophoresis tanks
- PCR Machines
- Gel documentation system
- Confocal microscope
- Incubator
- pH meter
- Cytospin
- DNA extraction
- PBL/ plasma/ serum isolation
- Microarray facility
- Genotyping
- DNA sequencing
- Microsatellite analysis
- Mass spectrometry
- Proteomics
- HPLC
- Radioisotope laboratory
- Gene therapy suite
- Other
- GCMP production facilities for cellular therapies (Head of National Blood Service overseeing all UK labs, based at John Radcliffe)
- All molecular biology techniques are essentially available at the WIMM; arrays for SNPs, RNA, CGH, mRNA, CHIP assays
- Plasma and serum analysis of DNA, RNA, micro RNA
- Molecular pathology including tissue microarrays
- Serial tumour biopsies
- FACs for endothelial cells
- DNA repair assays-COMET
- Immunological monitoring - ELISPOT, tetramers
- Structural and kinetic analysis of HLA calls I/ peptide and CD1d/ glycolipid interaction to optimise T and NKT cell responses
- GCMP production of dendritic cells
- Production of viral vectors to GLP
- MRI scanner
- Other
- SPECT
- A CT PET scanner and cyclotron will be available in the new Oxford Cancer Centre
- DCE MRI for vascular permeability studies
- Radioisotope localisation studies, antibody and peptide labelling for imaging and therapy
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